Endocrine Abstracts

Clinical case: We report the case of a 40-year-old woman, diagnosed with sporadic medullary thyroid carcinoma (MTC) treated with total thyroidectomy, cervical lymph node dissection and chemotherapy. During follow-up, cervical lymph node, lung, breast, bone and subcentimeter cerebellous affectation was observed. She started on Sunitinib, but withdrawal at 6 months due to severe inguinal inverse psoriasis. Then, treatment with vandetanib was started with good response. Tumor mar...

Background: Despite a high relapse rate, antithyroid drugs (ATDs) remain the first-line therapy of Graves’ disease (GD). Long-term follow-up studies of GD in Spain are scarce. Our aims were to identify clinical differences between patients who relapsed vs those who attained remission and to describe the relapse rate of GD after ATD withdrawal.Methods: We analyzed patients with the first episode of GD who were treated with ATDs during 2010 - 2020, in...

Introduction: Different pharmacological therapies for obesity have become available in the last years. It is important to know their effectiveness in real-world practice and their acceptance among patients.Objectives: To analyze the anthropometric changes, daily dosis, side effects and treatment withdrawal in patients treated with Liraglutide or Naltrexone/Bupropion in clinical practice.Material and methods: Retrospective descripti...

Introduction: Real-world data on glucose and weight control effectiveness in patients with Type 2 diabetes mellitus (T2DM) on treatment with semaglutide is scarce. We aim to assess it in a cohort of patients from a real-world setting in Spain.Materials and methods: We identified 830 patients with T2DM that were prescribed Semaglutide once-weekly since May 2019 to December 2020, in 4 hospitals in Madrid-Spain. At 6±3 months, 435 GPL1-naïve and 3...

Objectives: To evaluate the changes in HbA1c, basal glucose, weight, and lipid profile in patients with type 2 diabetes after starting oral semaglutide.Methods: This study was conducted in Madrid, Fundación Jiménez Díaz, Infanta Elena and General de Villalba hospitals. A total of 75 patients with type 2 diabetes were included. The mean age was 62.0±10.5 years and 60% were men. The mean duration of diabetes was 7.3±6.6 years, and 66.7...

IntroductionGlucose and weight control effectiveness in patients with Type 2 diabetes (T2D) in treatment with DPP4 inhibitors (DPP4i) that switch to semaglutide is scarce. We aim to assess it in a real-world setting of DPP4i-experienced patients and compare it to DPP4i-naive patients.MethodsPatients with T2D that were prescribed Once-Weekly semaglutide in 4 hospitals in Madrid-Spain were identified. Patients ...